Full Schedule

7:00 AM – 8:00 AM CEST

Regional Interest Groups

7:00 AM – 8:00 AM CEST

Coffee with Exhibitors

Location: Hall C

7:00 AM – 8:00 AM CEST

Poster Session B Set-Up

Location: Hall C

7:00 AM – 6:00 PM CEST

Lactation Room

Location: Meeting Room 28

7:00 AM – 6:00 PM CEST

Registration

Location: Hall F6-F7 Lobby

7:00 AM – 6:00 PM CEST

Speaker Ready Room

Location: Meeting Room 21

8:00 AM – 9:30 AM CEST

Methods for Generating RWE Through Emulation of Target Trials

Location: C1M5

Moderator: – Rutgers Center for Pharmacoepidemiology and Treatment Science

Moderator: – Aetion, Inc

Methods in Pharmacoepidemiology

8:00 AM – 8:15 AM CEST

One Design to Rule Them All: The Clone-Censor-Weight Design as a General Framework for Epidemiologic Studies

Location: C1M5

Presenting Author: – Target RWE

Methods in Pharmacoepidemiology

8:15 AM – 8:30 AM CEST

Effect of Different Durations of Treatment with Antihypertensive Drugs with Anticholinergic Effects on the Risk of Dementia: A Target Trial Emulation Study

Location: C1M5

Presenting Author: – RTI Health Solutions

Co-Author: – RTI Health Solutions

Methods in Pharmacoepidemiology

8:30 AM – 8:45 AM CEST

Evaluation Metrics for Data-driven Propensity Score Estimation: A Simulation Study

Location: C1M5

Presenting Author: – CSM, NDORMS, University of Oxford

Co-Author: – CSM, NDORMS, University of Oxford

Co-Author: – Boehringer Ingelheim Pharma GmbH & Co. KG

Co-Author: – CSM, NDORMS, University of Oxford

Methods in Pharmacoepidemiology

8:45 AM – 9:00 AM CEST

Emulating a Sequence of Target Trials to Avoid Immortal Time Bias in Pregnancy Studies — an Application to Antibiotic Initiation and Preterm Delivery

Location: C1M5

Presenting Author: – University of Pennsylvania Perelman School of Medicine

Co-Author: – Beth Israel Deaconess Medical Center

Co-Author: – Harvard T.H. Chan School of Public Health

Co-Author: – Botswana Harvard AIDS Institute Partnership

Co-Author: – University of Pennsylvania Perelman School of Medicine

Co-Author: – Botswana Harvard AIDS Institute Partnership

Co-Author: – Harvard T.H. Chan School of Public Health

Co-Author: – University of Pennsylvania Perelman School of Medicine

Co-Author: – Boston University School of Public Health

Co-Author: – Harvard School of Public Health

Co-Author: – Harvard T.H. Chan School of Public Health

Methods in Pharmacoepidemiology

9:00 AM – 9:15 AM CEST

Comparing the Effects of Neoadjuvant versus Adjuvant Chemotherapy in Stage II-III, Triple-negative Breast Cancer: Illustration of Trial Emulation Using the Clone-Censor-Weight Method

Location: C1M5

Presenting Author: – University of North Carolina at Chapel Hill

Co-Author: – University of Illinois-Chicago

Co-Author: – Memorial Sloan Kettering Cancer Center

Co-Author: – UNC Gillings School of Global Public Health

Methods in Pharmacoepidemiology

9:15 AM – 9:30 AM CEST

Emulating Stratified Randomized Trials by Propensity Score Methods

Location: C1M5

Presenting Author: – Brigham and Women's Hospital/Harvard Medical School

Co-Author: – Harvard Medical School, Brigham and Women's Hospital

Co-Author: – Harvard Medical School/Brigham & Women's Hospital

Co-Author: – Brigham and Women's Hospital, Harvard Medical School

Co-Author: – BWH Div of Pharmacoepidemiology and Pharmacoeconomics

Co-Author: – Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA

Methods in Pharmacoepidemiology

8:00 AM – 9:30 AM CEST

Drug Utilization Potpourri

Location: Congress Hall D2

Moderator: – University of Sorocaba, S�o Paulo, Brazil

Moderator: – University of Uppsala

Drug Utilization Research

8:00 AM – 8:15 AM CEST

Method of Hormonal Contraception and Protective Effects Against Ectopic Pregnancy: A Population-based Register Study

Location: Congress Hall D2

Presenting Author: – Karolinska Institutet

Co-Author: – Karolinska Institutet

Co-Author: – Department of Clinical Sciences at Danderyd Hospital, Karolinska Institute, SE-171 77 Stockholm, Sweden

Co-Author: – Department of Medicine Solna, Center for Pharmacoepidemiology, Karolinska Institutet, Stockholm, Sweden

Co-Author: – Center for Pharmacoepidemiology, Karolinska Insitutet

Drug Utilization Research

8:15 AM – 8:30 AM CEST

The Characteristics of Gabapentinoid Users with Chronic Non-cancer Pain in the Primary Care of United Kingdom

Location: Congress Hall D2

Presenting Author: – The University of Manchester

Co-Author: – the University of Manchester

Co-Author: – University of Manchester

Drug Utilization Research

8:30 AM – 8:45 AM CEST

Sedative Load Before and After Entry to Residential Aged Care

Location: Congress Hall D2

Presenting Author: – University of South Australia

Co-Author: – Registry of Senior Australians, South Australian Health and Medical Research Institute

Drug Utilization Research

8:45 AM – 9:00 AM CEST

Prescription Patterns in Patients with Incident Trigeminal Neuralgia

Location: Congress Hall D2

Presenting Author: – University of Florida Department of Pharmaceutical Outcomes and Policy

Co-Author: – University of Florida

Co-Author: – Department of Pharmaceutical Outcomes and Policy, College of Pharmacy, University of Florida

Co-Author: – University of North Carolina at Chapel Hill

Drug Utilization Research

9:00 AM – 9:15 AM CEST

Non-adherence to Chronic Medications Used in COPD and Its Association with Adverse Events: A Longitudinal, Population Based Study

Location: Congress Hall D2

Presenting Author: – Utrecht University

Co-Author: – University of Toronto

Co-Author: – Ottawa Hospital Research Institute

Co-Author: – University of Toronto

Co-Author: – Ottawa Hospital

Co-Author: – University of Toronto

Drug Utilization Research

9:15 AM – 9:30 AM CEST

South Peace Polypharmacy Reduction Project: Impact Evaluations of Medication Reviews and Online Workshops in Rural British Columbia

Location: Congress Hall D2

Presenting Author: – University of British Columbia

Co-Author: – University of British Columbia

Drug Utilization Research

8:00 AM – 9:30 AM CEST

Opioids and Addiction - The Other Pandemic?

Location: Congress Hall D5

Moderator: – The Ohio State University

Moderator: – Pharmaceutical Health Services Research, School of Pharmacy

Drug Utilization Research

8:00 AM – 8:15 AM CEST

Trajectories of Use in Elderly Incident Benzodiazepine Users of Norway

Location: Congress Hall D5

Presenting Author: – University of Tromso

Drug Utilization Research

8:15 AM – 8:30 AM CEST

Patterns of Buprenorphine Initiation Treatment for Opioid Use Disorder and Association with Opioid-related Overdose Deaths

Location: Congress Hall D5

Presenting Author:

Co-Author: – University of Kentucky College of Public Health

Co-Author: – University of Kentucky College of Pharmacy

Co-Author: – Department of Biostatistics, College of Public Health, University of Kentucky

Co-Author: – Institute for Biomedical Informatics, College of Medicine, University of Kentucky

Co-Author: – UNC Gillings School of Global Public Health

Co-Author: – Departments of Behavioral Science and Psychiatry, University of Kentucky

Co-Author: – University of Kentucky

Co-Author: – University of North Carolina at Chapel Hill

Drug Utilization Research

8:30 AM – 8:45 AM CEST

Secular Trends of Dispensed Opioid Prescriptions in Catalonia, Spain, 2007-19: A Population-based Cohort Study of over 5 Million Individuals

Location: Congress Hall D5

Presenting Author: – CSM, NDORMS, University of Oxford

Co-Author: – Boehringer Ingelheim Pharma GmbH & Co. KG

Co-Author: – Centre for Statistics in Medicine, Nuffield Department of Orthopaedics, Rheumatology & Musculoskeletal Sciences, University of Oxford, Oxford, UK

Co-Author: – CSM, NDORMS, University of Oxford

Co-Author: – Pharmaco- and Device Epidemiology, Centre for Statistics in Medicine - Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, Botnar Research Centre, University of Oxford, Windmill Road, Oxford

Co-Author: – 4. Clinical Epidemiology Unit, Orthopaedics, Clinical Sciences, Lund, Lund University, Lund, Sweden

Co-Author:

Co-Author: – Institut Universitari d�Investigaci� en Atenci� Prim�ria Jordi Gol

Co-Author: – CSM, NDORMS, University of Oxford

Drug Utilization Research

8:45 AM – 9:00 AM CEST

Association of Opioid Dose Reduction with Opioid Overdose and Opioid Use Disorder Among Patients on High-dose Long-term Opioid Therapy in North Carolina

Location: Congress Hall D5

Presenting Author: – University of North Carolina at Chapel Hill

Co-Author: – Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, North Carolina, USA

Co-Author: – UNC Gillings School of Global Public Health

Co-Author: – Injury Prevention Research Center, University of North Carolina, Chapel Hill, North Carolina, USA

Co-Author: – Department of Medicine, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA

Co-Author: – Injury Prevention Research Center, University of North Carolina, Chapel Hill, North Carolina, USA

Co-Author: – Department of Medicine, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA

Co-Author: – UNC Gillings School of Global Public Health

Co-Author: – Department of Health Behavior, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, North Carolina, USA

Co-Author: – Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, North Carolina, USA

Drug Utilization Research

9:00 AM – 9:15 AM CEST

Geographic Variation of High-risk Prescription Opioid Use Measures Among Disabled Medicare Beneficiaries, 2011-2018

Location: Congress Hall D5

Presenting Author: – University of Florida Department of Pharmaceutical Outcomes and Policy

Co-Author: – BeiGene

Co-Author: – Center for Pharmaceutical Policy and Prescribing, Health Policy Institute, University of Pittsburgh

Co-Author: – University of North Carolina at Chapel Hill

Co-Author: – Biobehavioral Nursing Science, University of Florida

Co-Author: – Department of Pharmaceutical Outcomes and Policy, College of Pharmacy, University of Florida

Co-Author: – University of Florida Department of Pharmaceutical Outcomes and Policy

Drug Utilization Research

9:15 AM – 9:30 AM CEST

The Association Between Trajectories of Prescription Opioid Use and Opioid Overdose Risk Among Nonmetastatic Breast Cancer Survivors

Location: Congress Hall D5

Presenting Author: – University of Florida Department of Pharmaceutical Outcomes and Policy

Co-Author: – University of North Carolina at Chapel Hill

Co-Author: – Department of Pharmaceutical Outcomes & Policy, College of Pharmacy, University of Florida

Co-Author: – University of Florida

Co-Author: – Department of Medicine, College of Medicine, University of Florida

Co-Author: – University of Florida

Co-Author: – Department of Pharmaceutical Outcomes and Policy, College of Pharmacy, University of Florida

Drug Utilization Research

8:00 AM – 9:30 AM CEST

Across the Globe: Injury and Neurologic Pharmacoepidemiology

Location: C1M0

Moderator: – IQVIA

Moderator: – RTI Health Solutions

Disease Epidemiology/Clinical Course

8:00 AM – 8:15 AM CEST

β2-adrenoceptor Agonists and Risk of Parkinson's Disease: Nested Case-control Study of People with Asthma or Chronic Obstructive Pulmonary Disease

Location: C1M0

Presenting Author:

Co-Author: – University of Eastern Finland

Co-Author: – Unit for Medicine and Clinical Research, Pulmonary Division, Kuopio University Hospital, Kuopio, Finland

Co-Author: – School of Pharmacy, University of Eastern Finland, Kuopio, Finland

Co-Author: – Department of Forensic Psychiatry, University of Eastern Finland, Niuvanniemi Hospital, Niuvankuja 65, FI-70240 Kuopio, Finland

Co-Author: – School of Pharmacy, University of Eastern Finland, Kuopio, Finland

Disease Epidemiology/Clinical Course

8:15 AM – 8:30 AM CEST

Trends in the Use of Non-prescription Medications for Intentional Self-poisoning: A Review of Data from the United States Poison Control Centers

Location: C1M0

Presenting Author: – US Food and Drug Administration

Co-Author: – DHHS/FDA

Co-Author: – U.S. Food and Drug Administration Center for Dug Evaluation and Research, Division of Epidemiology, Silver Spring MD

Co-Author: – US Food and Drug Administration

Disease Epidemiology/Clinical Course

8:30 AM – 8:45 AM CEST

Dosing Profiles of Opioid and Benzodiazepine Use Associated with Risk of Injurious Falls Among US Medicare Beneficiaries: Group-based Multi-trajectory Models

Location: C1M0

Presenting Author: – University of North Carolina at Chapel Hill

Co-Author: – Center for Pharmaceutical Policy and Prescribing, Health Policy Institute, University of Pittsburgh

Co-Author: – Department of Pharmaceutical Outcomes & Policy, College of Pharmacy, University of Florida

Co-Author: – Department of Pharmacy Practice and Science, College of Pharmacy, University of Arizona

Co-Author: – Department of Pharmaceutical Outcomes & Policy, College of Pharmacy, University of Florida

Co-Author: – Department of Pharmaceutical Outcomes and Policy, College of Pharmacy, University of Florida

Co-Author: – Divisions of Addiction Medicine & Forensic Psychiatry, Departments of Psychiatry & Anesthesiology, College of Medicine, University of Florida

Co-Author: – University of Arizona Arthritis Center, College of Medicine, University of Arizona

Co-Author: – Department of Pharmacotherapy & Translational Research, College of Pharmacy, University of Florida

Co-Author: – Pharmacy Practice & Science, Institute for Pharmaceutical Outcomes & Policy, College of Pharmacy, University of Kentucky

Co-Author: – Department of Health Outcomes and Biomedical Informatics, College of Medicine, University of Florida

Co-Author: – Department of Management Information Systems, University of Arizona

Co-Author: – North Florida/South Georgia Veterans Health System Geriatric Research Education and Clinical Center

Co-Author: – School of Pharmacy, University of Washington

Co-Author: – University of Florida College of Pharmacy

Co-Author: – Department of Pharmaceutical Outcomes and Policy, College of Pharmacy, University of Florida

Co-Author: – Health Science Center Libraries, University of Florida

Co-Author: – University of Florida Department of Pharmaceutical Outcomes and Policy

Geriatric Pharmacoepidemiology

8:45 AM – 9:00 AM CEST

Bacillus Calmette-Guérin Therapy for Bladder Cancer and Risk of Alzheimer's Disease in Denmark

Location: C1M0

Presenting Author: – Department of Clinical Epidemiology, Aarhus University

Co-Author: – Department of Clinical Epidemiology, Department of Clinical Medicine, Aarhus University Hospital and Aarhus University

Co-Author: – Department of Clinical Epidemiology, Aarhus University

Co-Author: – Department of Urology, Aarhus University Hospital and Department of Clinical Medicine, Aarhus University

Disease Epidemiology/Clinical Course

9:00 AM – 9:15 AM CEST

Effect of Reductions in Opioid Prescribing on Opioid Use Disorder and Fatal Overdose in the United States: A Dynamic Markov Model

Location: C1M0

Presenting Author: – JHSPH Center for Drug Safety & Effectiveness

Co-Author: – Johns Hopkins Bloomberg School of Public Health

Co-Author: – Harvard School of Public Health

Co-Author: – Johns Hopkins Bloomberg School of Public Health

Disease Epidemiology/Clinical Course

9:15 AM – 9:30 AM CEST

Fatal Overdoses in a Cohort of Chronic Pain Patients

Location: C1M0

Presenting Author: – University of Oslo

Co-Author: – Department of Mental Disorders, Norwegian Institute of Public Health

Co-Author: – Norwegian Institute of Public Health

Co-Author: – Center for Alcohol and Drug Research at Stavanger University Hospital

Co-Author: – Norwegian Centre for Addiction Research, Institute of Clinical Medicine, University of Oslo

Co-Author: – Department of Mental Disorders, Norwegian Institute of Public Health, Norway

Disease Epidemiology/Clinical Course

8:00 AM – 9:30 AM CEST

Safety First!

Location: C1M1

Moderator: – University of Florida

Safety End Points

8:00 AM – 8:15 AM CEST

Use of Antipsychotics and the Risk of Acute Respiratory Failure

Location: C1M1

Presenting Author:

Co-Author: – Pharmaceutical Health Services Research, School of Pharmacy

Safety End Points

8:15 AM – 8:30 AM CEST

Evaluating the Long-term Effect of Allopurinol Use in Gout Using Marginal Structural Models: A Primary Care Electronic Health Records Study

Location: C1M1

Presenting Author: – CSM, NDORMS, University of Oxford

Co-Author: – Primary Care Centre Versus Arthritis, School of Medicine, Keele University, Keele, UK

Drug Effectiveness

8:30 AM – 8:45 AM CEST

Association Between Fluoroquinolones and Uveitis, Retinal Detachment and Aortic Aneurysm or Dissection: An Application of Self-controlled Study Designs with Active Comparators

Location: C1M1

Presenting Author: – London School of Hygiene and Tropical Medicine

Co-Author: – Department of Non-Communicable Disease Epidemiology, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT

Co-Author: – Department of Medical Statistics, London School of Hygiene and Tropical Medicine

Co-Author: – Department of Medical Statistics, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT

Co-Author: – London School of Hygiene & Tropical Medicine

Co-Author: – London School of Hygiene and Tropical Medicine

Co-Author: – Tennet Institute of Ophthalmology, Gartnavel General Hospital, Glasgow, UK

Co-Author: – Research Statistics, GSK, Stevenage, UK

Co-Author: – Department of Non-Communicable Disease Epidemiology, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT

Safety End Points

8:45 AM – 9:00 AM CEST

Death, Cardiac Event and Acute Liver Injury Associated with Bedaquiline or Delamanid in Patients with Multidrug Resistant Tuberculosis: A Nationwide Cohort Study

Location: C1M1

Presenting Author: – School of Pharmacy, Sungkyunkwan University

Co-Author: – School of Pharmacy - Sungkyunkwan University

Co-Author: – Sungkyunkwan University

Co-Author: – School of Pharmacy, Sungkyunkwan University

Safety End Points

9:00 AM – 9:15 AM CEST

Risk of depressive disorders associated with medical cannabis authorization: a propensity score matched cohort study

Location: C1M1

Presenting Author: – 1 Faculty of Pharmacy, Université Laval, Quebec City, QC, Canada. 2 Population Health and Optimal Health Practices Research Unit, CHU de Québec, Université Laval Research Centre, Quebec City, QC, Canada

Co-Author: – Cardiovascular Research Centre, Department of Pediatrics, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, AB, Canada

Co-Author: – School of Public Health, University of Alberta, Edmonton, AB, Canada

Co-Author: – Population Health and Optimal Health Practices Axis, CHU de Québec-Université Laval Research Center, Québec, Québec, Canada

Safety End Points

9:15 AM – 9:30 AM CEST

Risk of Mortality Associated with Pimavanserin Compared with Atypical Antipsychotics in Patients with Parkinson's Disease—related Psychosis

Location: C1M1

Presenting Author: – RTI Health Solutions

Co-Author: – RTI Health Solutions

Co-Author: – Acadia Pharmaceuticals

Co-Author: – RTI Health Solutions

Co-Author: – Acadia Pharmaceuticals

Safety End Points

8:00 AM – 9:30 AM CEST

Disease Epidemiology Potpourri

Location: C1M2

Moderator: – NPO Drug Safety Research Unit Japan

Moderator: – Mercer Univ Sch of Pharm

Disease Epidemiology/Clinical Course

8:00 AM – 8:15 AM CEST

Inhaled Corticosteroids and COVID-19 Risk and Outcomes — Findings from a Population-based Cohort Within the SCIFI-PEARL Project

Location: C1M2

Presenting Author: – University of Gothenburg

Co-Author: – Cancer and Lung Health Care Unit, University Hospital in Linköping, Sweden.

Co-Author: – University of Gothenburg

Co-Author: – COPD Center, Department of Respiratory Medicine and Allergology, Sahlgrenska University Hospital, Gothenburg, Sweden

Disease Epidemiology/Clinical Course

8:15 AM – 8:30 AM CEST

Risk Factors for Mortality and Intensive Care Requirements Among Pediatric Patients Hospitalized with COVID-19 in the United States

Location: C1M2

Presenting Author: – Target RWE

Co-Author: – Target RWE

Co-Author: – NoviSci, Inc.

Co-Author: – Target RWE

Co-Author: – Duke University

Disease Epidemiology/Clinical Course

8:30 AM – 8:45 AM CEST

Temporal Trends, In-hospital Outcomes and Comorbidity Profile in US Asthma Hospitalizations Between 2004 and 2017

Location: C1M2

Presenting Author: – Division of Population Health, Health Services Research & Primary Care, University of Manchester

Co-Author: – Keele University

Co-Author: – Keele Cardiovascular Research Group, Centre for Prognosis Research, Institute for Primary Care and Health Sciences, Keele University, Keele, UK

Co-Author: – Division of Informatics, Imaging and Data Sciences, School of Health Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre (MAHSC), University of Manchester, Manchester M13 9PL, UK

Disease Epidemiology/Clinical Course

8:45 AM – 9:00 AM CEST

Healthcare Costs and Disease Duration Associated with Mild, Moderate and Severe COVID-19: A Payer Perspective

Location: C1M2

Presenting Author: – Johnson & Johnson

Co-Author: – Janssen

Co-Author: – Johnson & Johnson

Co-Author: – Mu Sigma

Co-Author: – Janssen

Co-Author: – University of Pennsylvania School of Medicine

Disease Epidemiology/Clinical Course

9:00 AM – 9:15 AM CEST

Clustering of HbA1c Longitudinal Trajectories in Type 2 Diabetes Mellitus (T2DM)

Location: C1M2

Presenting Author: – ETH Zurich

Co-Author: – Swiss Federal Institute of Technology

Co-Author: – Swiss Data Science Center, ETH Zurich and EPFL, Switzerland

Co-Author: – Institute of Pharmaceutical Sciences, Department of Chemistry and Applied Biosciences, ETH Zurich, Zurich, Switzerland.

Co-Author: – Institute of Pharmaceutical Sciences, Department of Chemistry and Applied Biosciences

Disease Epidemiology/Clinical Course

9:15 AM – 9:30 AM CEST

Women's Mortality Following Childbirths Affected by Vaginal Bleeding Due to Threatened Miscarriage: A Danish Cohort Study with up to 40 Years of Follow-up

Location: C1M2

Presenting Author: – Aarhus University

Co-Author:

Co-Author: – Department of Clinical Epidemiology, Aarhus University and Aarhus University Hospital, Aarhus, Denmark

Co-Author: – Aarhus University

Disease Epidemiology/Clinical Course

8:00 AM – 6:00 PM CEST

Exhibits/Poster Session B

Location: Hall C

9:30 AM – 10:00 AM CEST

Break/Exhibits/Posters

Location: Hall C

10:00 AM – 11:30 AM CEST

Updates from the COVID-19 Pharmacoepidemiological Battlefield: Recent Victories and Battles Ahead [Plenary]

Location: Congress Hall D4

Lead Speaker: – University of Southern Denmark

Speaker: – CSM, NDORMS, University of Oxford

Speaker: – RTI Health Solutions

Speaker: – University Medical Center Utrecht

Speaker: – European Medicines Agency

11:30 AM – 1:00 PM CEST

Committee Meetings

11:30 AM – 1:00 PM CEST

Lunch/Exhibits/Posters

Location: Hall C

11:45 AM – 12:45 PM CEST

Spotlight Poster Session B

Location: Hall E-South

1:00 PM – 2:30 PM CEST

Methods: Machines Making Predictions

Location: Congress Hall D4

Moderator: – Optum Epidemiology

Moderator: – IQVIA

Methods in Pharmacoepidemiology

1:00 PM – 1:15 PM CEST

Comparative Evaluation of Automated Approaches for Confounder Selection in Ultra High-dimensional Data with Rare Outcomes

Location: Congress Hall D4

Presenting Author: – Brigham and Women's Hospital, Harvard Medical School

Co-Author: – University of California, Berkeley

Co-Author: – Putnam Data Sciences

Co-Author: – University of Michigan

Co-Author: – U.S. Food and Drug Administration

Co-Author: – Harvard Pilgrim Health Care Institute

Co-Author: – Kaiser Permanente Washington Health Research Institute

Co-Author: – Harvard Medical School/Brigham & Women's Hospital

Co-Author:

Methods in Pharmacoepidemiology

1:15 PM – 1:30 PM CEST

Fracture Risk Estimation in Post-menopausal Women: A Comparison of Machine Learning Methods and Software Systems

Location: Congress Hall D4

Presenting Author: – Target RWE

Co-Author: – NoviSci, LLC

Co-Author: – Duke University

Methods in Pharmacoepidemiology

1:30 PM – 1:45 PM CEST

A New Artificial Intelligence Guided Method for Identifying Add-on and Switch in Secondary Data Sources: A Case Study on Antiseizure Medications in Danish Registries

Location: Congress Hall D4

Presenting Author: – University of Copenhagen

Methods in Pharmacoepidemiology

1:45 PM – 2:00 PM CEST

Claims-based Model to Predict Obesity in Older Patients

Location: Congress Hall D4

Presenting Author: – Brigham and Women's Hospital, Harvard Medical School

Co-Author: – Division of Pharmacoepidemiology and Pharmacoeconomics

Co-Author: – Brigham and Women's Hospital, Harvard Medical School

Co-Author: – Brigham and Women's Hospital

Co-Author: – Brigham and Women's Hospital, Harvard Medical School

Co-Author:

Methods in Pharmacoepidemiology

2:00 PM – 2:15 PM CEST

Development of a Multivariate Prediction Model to Identify Possible Signal Triggering Reports from Spontaneous Individual Case Safety Reports

Location: Congress Hall D4

Presenting Author: – Netherlands Pharmavigilance Centre Lareb

Co-Author: – Netherlands Pharmacovigilance Centre Lareb, 's-Hertogenbosch, The Netherlands

Methods in Pharmacoepidemiology

2:15 PM – 2:30 PM CEST

Predicting Wilson Disease Progression Using Machine Learning with Real-world Electronic Health Records

Location: Congress Hall D4

Presenting Author: – Pfizer Inc

Co-Author: – Pfizer Inc

Co-Author: – Pfizer, Global Medical Epidemiology

Co-Author: – Pfizer, Global Product Development

Co-Author: – Pfizer, Worldwide Research and Development

Co-Author: – Pfizer Inc

Methods in Pharmacoepidemiology

1:00 PM – 2:30 PM CEST

Study Design Approaches to Assessing Thrombosis Risk

Location: Congress Hall D2

Moderator: – ASL Roma 1 Regione Lazio

Moderator: – Rutgers Institute for Health, Health Care Policy and Aging Research

Disease Epidemiology/Clinical Course

1:00 PM – 1:15 PM CEST

Risk of Venous Thromboembolism in Patients Receiving Targeted Anti-cancer Therapy - A Nationwide Cohort Study

Location: Congress Hall D2

Presenting Author:

Co-Author: – Clinical Division of Haematology and Haemostaseology, Department of Medicine I, Comprehensive Cancer Center Vienna, Medical University of Vienna, Vienna, Austria

Co-Author: – Thrombosis Research Center, Department of clinical medicine, UiT – The Arctic university of Norway and University Hospital of North Norway, Tromsø, Norway

Co-Author: – Department of Vascular Medicine, Amsterdam Cardiovascular Science, Amsterdam University Medical Center, University of Amsterdam, Amsterdam, The Netherlands

Co-Author: – Department of Clinical Epidemiology, Aarhus University and Aarhus University Hospital, Aarhus, Denmark

Safety End Points

1:15 PM – 1:30 PM CEST

Arterial and Venous Thrombotic Events in Patients with COVID-19 Compared to Influenza

Location: Congress Hall D2

Presenting Author: – Harvard Pilgrim Health Care Institute

Co-Author: – U.S. Food and Drug Administration

Co-Author: – Harvard Pilgrim Health Care Institute

Co-Author: – US Food and Drug Administration

Co-Author: – University of Pennsylvania

Co-Author: – HealthPartners Institute

Co-Author: – CVS Health Clinical Trials Services

Co-Author: – Kaiser Permanente Washington Health Research Institute

Co-Author: – Harvard Pilgrim Health Care Institute

Co-Author: – Department of Biostatistics, Epidemiology and Informatics, Perelman School of Medicine, The University of Pennsylvania

Co-Author: – 1Department of Biostatistics, Epidemiology and Informatics, Perelman School of Medicine, The University of Pennsylvania

Co-Author: – Harvard Pilgrim Health Care Institute

Co-Author: – Kaiser Permanente Center for Health Research

Co-Author: – CVS Health Clinical Trial Services

Co-Author: – Harvard Pilgrim Health Care Institute

Co-Author: – HealthPartners Institute

Co-Author: – Harvard Pilgrim Health Care Institute

Co-Author: – University of Pennsylvania

Co-Author: – Harvard Pilgrim Health Care Institute

Co-Author: – Kaiser Permanente Colorado Institute for Health Research

Co-Author: – Humana Healthcare Research, Inc.

Co-Author: – UPenn Center for Pharmacoepidemiology Research & Training

Disease Epidemiology/Clinical Course

1:30 PM – 1:45 PM CEST

Synergistic Effects of PM2.5 and Use of Corticosteroids on Cardiovascular and Thromboembolic Events Among Older Adults: Evidence of Environment-Drug Interaction

Location: Congress Hall D2

Presenting Author: – Harvard School of Public Health

Co-Author: – Harvard T.H. Chan School of Public Health

Co-Author: – Rutgers Robert Wood Johnson Medical School

Co-Author: – Rutgers University

Co-Author: – Rutgers University Institute for Health

Co-Author: – Rutgers Robert Wood Johnson Medical School

Safety End Points

1:45 PM – 2:00 PM CEST

Association Between Phentermine and Risk of Major Adverse Cardiovascular Events: A Suite of Self-Controlled and Comparative Cohort Studies to Conquer Confounding

Location: Congress Hall D2

Presenting Author: – University of Florida Department of Pharmaceutical Outcomes and Policy

Co-Author: – Regeneron Pharmaceuticals

Co-Author: – 4. Division of Endocrinology, Diabetes, & Metabolism, College of Medicine, University of Florida

Co-Author: – Center for Drug Evaluation and Safety, Department of Pharmaceutical Outcomes & Policy, University of Florida College of Pharmacy, Gainesville, FL USA

Co-Author: – University of Florida

Safety End Points

2:00 PM – 2:15 PM CEST

Use of Chlorprothixene and the Risk of Diabetes and Major Adverse Cardiovascular Events: A Nation-wide Cohort Study

Location: Congress Hall D2

Presenting Author: – University of Southern Denmark

Co-Author: – University of Southern Denmark

Co-Author: – Mental Health Center Glostrup, Copenhagen University Hospital, Mental Health Services CPH, Copenhagen, Denmark

Co-Author: – Department of Psychiatry Odense – University Clinic, Mental Health Services in the Region of Southern Denmark, Odense, Denmark

Co-Author: – Psychiatric Centre Copenhagen, Mental Health Services in the Capital Region of Denmark, Copenhagen, Denmark

Safety End Points

2:15 PM – 2:30 PM CEST

Use of Combined Oral Contraceptives and Risk of Venous Thromboembolism: A Nested Case-control Analysis in German Claims Data

Location: Congress Hall D2

Presenting Author: – Leibniz Institute for Prevention Research and Epidemiology - BIPS

Co-Author: – Leibniz Institute for Prevention Research and Epidemiology - BIPS

Co-Author: – Department of Biometry and Data Management, Leibniz-Institut für Präventionsforschung und Epidemiologie - BIPS

Co-Author: – Leibniz Institute for Prevention Research and Epidemiology - BIPS

Safety End Points

1:00 PM – 2:30 PM CEST

What's the Risk? Cancer Risk & Common Medications

Location: Congress Hall D5

Moderator: – AstraZeneca

Moderator: – Ultragenyx Pharmaceutical Inc.

Disease Epidemiology/Clinical Course

1:00 PM – 1:15 PM CEST

5-alpha Reductase Inhibitor Use and Risk of Colorectal Cancer in Men with Benign Prostatic Hyperplasia: A Population-based Cohort Study

Location: Congress Hall D5

Presenting Author: – Queen's University of Belfast (Centre for Public Health)

Co-Author: – Queen's University Belfast, Belfast, Northern Ireland

Co-Author: – University of Aberdeen, Aberdeen, Scotland

Co-Author: – Belfast City Hospital, Belfast, UK

Co-Author: – McGill University, Montreal, Quebec, Canada

Co-Author: – Queen’s University Belfast, Belfast, Northern Ireland

Disease Epidemiology/Clinical Course

1:15 PM – 1:30 PM CEST

Parity, Use of Statins and Low-dose Aspirin, and Breast Cancer Risk — Data from Two Large Cohort Studies

Location: Congress Hall D5

Presenting Author: – Department of Clinical Epidemiology, Aarhus University

Co-Author: – Paris-Saclay University, UVSQ, Inserm, Gustave Roussy, "Exposome and Heredity" team, CESP, F-94805, Villejuif, France

Co-Author: – International agency for research on cancer

Co-Author: – Department of Clinical Epidemiology, Department of Clinical Medicine, Aarhus University and Aarhus University Hospital, Aarhus, Denmark

Co-Author: – Department of Clinical Epidemiology, Aarhus University and Aarhus University Hospital, Aarhus, Denmark

Co-Author: – Nutrition and Metabolism Branch, International Agency for Research on Cancer, Lyon, France

Co-Author: – Department of Clinical Epidemiology, Department of Clinical Medicine, Aarhus University and Aarhus University Hospital, Aarhus, Denmark

Disease Epidemiology/Clinical Course

1:30 PM – 1:45 PM CEST

Statins and Breast Cancer Recurrence: A Danish Nationwide Cohort Study with up to 23 Years of Follow-up

Location: Congress Hall D5

Presenting Author: – Department of clinical epidemiology, Aarhus University & Aarhus University Hospital

Co-Author: – Department of Clinical Epidemiology, Department of Clinical Medicine, Aarhus University and Aarhus University Hospital, Aarhus, Denmark

Co-Author: – Danish Cancer Society Research Center, Copenhagen, Denmark

Co-Author: – Danish Cancer Society

Co-Author: – Department of Oncology, Rigshospitalet, Copenhagen University, Copenhagen, Denmark

Co-Author: – Department of Surgery and Biochemistry, Larner College of Medicine, University of Vermont, Burlington, VT, USA

Co-Author: – Department of Clinical Epidemiology, Aarhus University

Co-Author: – Department of Clinical Epidemiology, Department of Clinical Medicine, Aarhus University and Aarhus University Hospital, Aarhus, Denmark

Disease Epidemiology/Clinical Course

1:45 PM – 2:00 PM CEST

The Association Between Menopausal Hormone Therapy and Gastric and Colorectal Cancer Risk in Korean Women: A Nationwide Population-based Cohort Study

Location: Congress Hall D5

Presenting Author: – Department of Biomedical Sciences, Seoul National University Graduate School, Seoul, Korea

Co-Author: – Northeastern Univ

Co-Author: – Seoul National University

Co-Author: – Institute of Health Policy and Management, Medical Research Center, Seoul National University, Korea

Co-Author: – Department of Oral Medicine and Oral Diagnosis, School of Dentistry and Dental Research Institute, Seoul National University, Korea

Co-Author: – Seoul National University College of Medicine

Disease Epidemiology/Clinical Course

2:00 PM – 2:15 PM CEST

Sodium-glucose Co-transporter 2 Inhibitors and the Risk of Early Bladder Cancer Events

Location: Congress Hall D5

Presenting Author: – Brigham and Women's Hospital, Harvard Medical School

Co-Author: – Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA

Co-Author: – The Lady Davis Research Institute, Centre for Clinical Epidemiology, Jewish General Hospital, QC, Canada

Co-Author: – Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA

Co-Author: – Queen’s University Belfast, Belfast, Northern Ireland

Co-Author: – Division of Endocrinology, Jewish General Hospital, Montreal, Québec, Canada

Co-Author: – McGill Dept of Epidemiology, Biostatistics and Occupational Health

Co-Author: – BWH Div of Pharmacoepidemiology and Pharmacoeconomics

Co-Author: – Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA

Co-Author: – McGill University, Montreal, Quebec, Canada

Safety End Points

2:15 PM – 2:30 PM CEST

Thiazide Diuretics and Risk of Colorectal Cancer

Location: Congress Hall D5

Presenting Author: – McGill Dept of Epidemiology, Biostatistics and Occupational Health

Co-Author: – Division of General Internal Medicine, Department of Medicine, McGill University Health Centre, Montreal

Co-Author: – Department of Epidemiology, Biostatistics, and Occupational Health, McGill University, Montreal

Co-Author: – Division of Clinical Pharmacy, the Hebrew University of Jerusalem, Jerusalem

Co-Author: – Department of Epidemiology, Biostatistics, and Occupational Health, McGill University, Montreal

Co-Author: – McGill University, Montreal, Quebec, Canada

Safety End Points

1:00 PM – 2:30 PM CEST

Psychotropic Use Around the World

Location: C1M0

Moderator: – Biogen

Moderator: – BWH Div of Pharmacoepidemiology and Pharmacoeconomics

Drug Utilization Research

1:00 PM – 1:15 PM CEST

Antidepressant Use Among Children and Adolescents Across the Scandinavian Countries

Location: C1M0

Presenting Author: – University of Southern Denmark

Co-Author: – Clinical Pharmacology, Pharmacy and Environmental Medicine, Department of Public Health, University of Southern Denmark, Denmark

Co-Author: – Centre for Pharmacoepidemiology, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden

Co-Author: – Centre for Pharmacoepidemiology, Clinical Epidemiology Division, Department of Medicine Solna, Karolinska Institute, Stockholm, Sweden

Co-Author: – Department of Chronic Diseases, Norwegian Institute of Public Health, Norway

Co-Author: – Department of Mental Disorders, Norwegian Institute of Public Health, Norway

Co-Author: – Department of Chronic Diseases, Norwegian Institute of Public Health, Norway

Co-Author: – Department of Clinical Pharmacology, Odense University Hospital, Denmark and Department of Clinical Research, University of Southern Denmark, Denmark

Co-Author: – University of Southern Denmark (Department of Clinical Research)

Co-Author: – University of Southern Denmark

Drug Utilization Research

1:15 PM – 1:30 PM CEST

Attention Deficit Hyperactivity Disorder Medication Consumption in 64 Countries from 2015 to 2019: A Longitudinal Study

Location: C1M0

Presenting Author: – The University of Hong Kong

Co-Author: – Laboratory of Data Discovery for Health (D24H), Hong Kong Science and Technology Park, Hong Kong

Co-Author: – Research Department of Practice and Policy, School of Pharmacy, University College London, London, United Kingdom

Co-Author: – Department of Paediatrics and Adolescent Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong

Co-Author: – Departments of Paediatrics and Psychiatry, Faculty of Medicine Dentistry and Health Sciences, University of Melbourne, Melbourne, Australia

Co-Author: – University of Hong Kong

Co-Author: – University College London (UCL)

Co-Author: – School of Pharmacy, Queen's University, Belfast, United Kingdom

Co-Author: – Research Department of Practice and Policy, School of Pharmacy, University College London, London, United Kingdom

Co-Author: – University of Groningen

Co-Author: – Department of Child and Adolescent Psychiatry, King's College London, Institute of Psychiatry, Psychology and Neuroscience, London, United Kingdom

Co-Author: – South London and Maudsley NHS Foundation Trust, Denmark Hill, Camberwell, London, United Kingdom

Co-Author: – Department of Social Work and Social Administration, Faculty of Social Sciences, The University of Hong Kong, Hong Kong

Co-Author: – University of Hong Kong

Co-Author: – Centre for Safe Medication Practice and Research, Department of Pharmacology and Pharmacy, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China

Drug Utilization Research

1:30 PM – 1:45 PM CEST

Patterns of ADHD Medicine Use: A Population-based Study Among Australian Children and Adults (2013-2020)

Location: C1M0

Presenting Author: – School of Population Health, UNSW Sydney

Co-Author: – National Drug and Alcohol Research Centre, Faculty of Medicine and Health, University of New South Wales, Sydney, Australia

Co-Author: – Centre for Big Data Research in Health, Faculty of Medicine and Health, University of New South Wales, Sydney, Australia

Co-Author: – Departments of Paediatrics and Psychiatry, Faculty of Medicine Dentistry and Health Sciences, University of Melbourne, Melbourne, Australia

Co-Author: – Centre for Big Data Research in Health, Faculty of Medicine and Health, University of New South Wales, Sydney, Australia

Co-Author: – Brain and Mind Centre, Children's Hospital Westmead Clinical School, Faculty of Medicine and Health, University of Sydney, Sydney, Australia

Co-Author: – Centre for Big Data Research in Health, Faculty of Medicine and Health, University of New South Wales, Sydney, Australia

Drug Utilization Research

1:45 PM – 2:00 PM CEST

An Overview of Psychotropic Pharmacotherapy at Time of Death by Suicide: An Australian-wide Case Series Study Using Administrative and Coronial Data

Location: C1M0

Presenting Author: – The University of Sydney

Co-Author: – University of Sydney

Co-Author: – Biomedical Informatics and Digital Health, The University of Sydney

Co-Author: – The University of Sydney

Co-Author: – Victorian Institute of Forensic Medicine

Co-Author: – Biomedical Informatics and Digital Health, The University of Sydney

Co-Author: – Centre for Big Data Research in Health

Co-Author: – University of Western Australia

Co-Author: – University of Oxford

Drug Utilization Research

2:00 PM – 2:15 PM CEST

Prescription of Psychotropic Medications in Patients with Cancer: A Population-based Study in Hong Kong

Location: C1M0

Presenting Author: – Chinese University of Hong Kong

Co-Author: – School of Pharmacy, Faculty of Medicine, The Chinese University of Hong Kong

Co-Author: – Li Chiu Kong Family Sleep Assessment Unit, Department of Psychiatry, Faculty of Medicine, The Chinese University of Hong Kong

Co-Author: – School of Pharmacy, Faculty of Medicine, The Chinese University of Hong Kong

Drug Utilization Research

2:15 PM – 2:30 PM CEST

Antidepressant Adherence Patterns over Time Among Adults with Depression — an Application of Group Based Trajectory Modeling Using Commercial Claims Data from 2007 — 2020

Location: C1M0

Presenting Author: – University of Maryland, Baltimore ISPE Student Chapter

Co-Author: – Department of Pharmaceutical Health Services Research, University of Maryland School of Pharmacy, Baltimore, MD, USA

Co-Author: – Pharmaceutical Health Services Research, School of Pharmacy

Drug Utilization Research

1:00 PM – 2:30 PM CEST

Mending Hearts and Brains

Location: C1M1

Moderator: – University of Gothenburg

Moderator: – Daiichi Sankyo

Drug Utilization Research

1:00 PM – 1:15 PM CEST

Comparative Effectiveness of Direct Oral Anticoagulants versus Warfarin Among Nursing Home Residents with Atrial Fibrillation

Location: C1M1

Presenting Author: – Bloomberg School of Public Health, Johns Hopkins University

Co-Author: – Johns Hopkins Bloomberg School of Public Health

Co-Author: – Johns Hopkins University

Co-Author: – The University of Texas Medical Branch

Co-Author: – JHSPH Center for Drug Safety & Effectiveness

Drug Effectiveness

1:15 PM – 1:30 PM CEST

The Effectiveness and Safety of Extended Anticoagulant Treatment in Patients with Venous Thromboembolism

Location: C1M1

Presenting Author: – Brigham and Women's Hospital/Harvard Medical School

Co-Author: – Harvard T.H. Chan School of Public Health

Co-Author: – Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA

Co-Author: – Brigham and Women's Hospital/Harvard Medical School

Co-Author: – BWH Div of Pharmacoepidemiology and Pharmacoeconomics

Drug Effectiveness

1:30 PM – 1:45 PM CEST

Using Real-world Data to Assess Comparative Effectiveness and Safety of Apixaban and Rivaroxaban in Patients with Nonvalvular Atrial Fibrillation in the UK

Location: C1M1

Presenting Author: – Aetion, Inc

Co-Author: – Aetion, Inc

Co-Author: – National Institute for Health and Care Excellence

Co-Author: – Aetion, Inc

Co-Author: – National Institute for Health and Care Excellence

Co-Author: – Aetion, Inc.

Drug Effectiveness

1:45 PM – 2:00 PM CEST

Prophylactic Anticoagulation with Low Molecular Weight Heparin in COVID-19: Cohort Studies in Denmark and Sweden

Location: C1M1

Presenting Author:

Co-Author: – Department of Medicine Solna, Karolinska Institute, Stockholm, Sweden

Co-Author: – Center for Clinical Research and Prevention, Copenhagen University Hospital, Bispebjerg and Frederiksberg, Copenhagen, Denmark

Co-Author: – Copenhagen Phase IV unit, Department of Clinical Pharmacology and Center for Clinical research and Prevention, Copenhagen University Hospital, Bispebjerg and Frederiksberg, Copenhagen, Denmark

Co-Author: – Department of Clinical Pharmacology, Copenhagen University Hospital Bispebjerg, Copenhagen, Denmark

Co-Author: – University of Southern Denmark

Co-Author: – Department of Infectious Diseases, Aalborg University Hospital, Aalborg, Denmark

Co-Author: – Department of Medicine Solna, Karolinska Institute, Stockholm, Sweden

Co-Author: – University of Southern Denmark

Co-Author: – Department of Clinical Pharmacology, Bispebjerg Hospital

Drug Effectiveness

2:00 PM – 2:15 PM CEST

Risk of Ischemic Stroke Associated with DOAC Discontinuation on Patients with Non-valvular Atrial Fibrillation

Location: C1M1

Presenting Author: – Universidad Complutense de Madrid

Co-Author: – Medical student

Co-Author: – Department of Public Health and Child Health. Faculty of Medicine. Universidad Complutense de Madrid

Co-Author: – Faculty of Medicine. Department of Public Health. Complutense University of Madrid

Co-Author: – BIFAP, Division of Pharmacoepidemiology and Pharmacovigilance, Spanish Agency for Medicines and Medical Devices (AEMPS), Madrid, Spain

Drug Effectiveness

2:15 PM – 2:30 PM CEST

High-intensity versus Low- or Moderate-intensity Statin Treatment for Patients with Ischemic Stroke: Nationwide Cohort Study

Location: C1M1

Presenting Author: – Department of Clinical Epidemiology, Aarhus University

Co-Author:

Co-Author: – Department of Clinical Epidemiology, Department of Clinical Medicine, Aarhus University & Aarhus University Hospital, Aarhus, Denmark

Co-Author: – Department of Clinical Epidemiology, Aarhus University

Co-Author:

Co-Author: – Department of Clinical Epidemiology, Aarhus University and Aarhus University Hospital, Aarhus, Denmark

Co-Author: – Department of Clinical Epidemiology, Department of Clinical Medicine, Aarhus University & Aarhus University Hospital, Aarhus, Denmark

Drug Effectiveness

1:00 PM – 2:30 PM CEST

Lightning Session 2

Location: C1M2

Moderator: – RTI Health Solutions

Moderator: – Department of Clinical Epidemiology, Aarhus University

Moderator: – Med Tech Epi, LLC

Moderator: – Kaiser Permanente Washington Health Research Institute

Lightning Session 2

1:00 PM – 1:05 PM CEST

Risk of Appendicitis After mRNA COVID-19 Vaccination: A Population-based Cohort Study

Location: C1M2

Presenting Author: – Pharmacology and Pharmacy, Department of Public Health, University of Southern Denmark (SDU)

Co-Author: – Clinical Pharmacology, Pharmacy and Environmental Medicine, University of Southern Denmark

Co-Author: – University of Southern Denmark

Co-Author: – Clinical Pharmacology, Pharmacy and Environmental Medicine, Department of Public Health, University of Southern Denmark, Denmark

Co-Author: – University of Southern Denmark

Co-Author: – Department of Clinical Pharmacology, Odense University Hospital, Denmark and Department of Clinical Research, University of Southern Denmark, Denmark

Co-Author: – University of Southern Denmark

Vaccines

1:05 PM – 1:10 PM CEST

Impact of Individual Case Reports for COVID-19 Vaccines on the Ability to Detect Future Safety Signals with Other Medicinal Products

Location: C1M2

Presenting Author: – Uppsala Monitoring Centre WHO Collaborating Centre for International Drug Monitoring

Co-Author: – Uppsala Monitoring Centre

Co-Author: – Uppsala Monitoring Centre WHO Collaborating Centre for International Drug Monitoring

Vaccines

1:10 PM – 1:15 PM CEST

The Impact of Data Truncation on Rates of Vaccine-Associated Adverse Events Utilizing Open and Closed Claims: Lessons from Post-Marketing Safety Surveillance of the SARS-CoV-2 mRNA-1273 Vaccine

Location: C1M2

Presenting Author: – Aetion, Inc

Co-Author: – Moderna

Co-Author: – Aetion, Inc

Co-Author: – Moderna, Inc

Co-Author: – Aetion, Inc

Co-Author: – Moderna, Inc

Vaccines

1:15 PM – 1:20 PM CEST

The Comparative Risk of Thrombosis with Thrombocytopenia Associated with Different COVID-19 Vaccines: International Network Cohort Study Including 5 European Countries and the US

Location: C1M2

Presenting Author: – Nuffield Department of Orthopaedics, Rheumatology, and Musculoskeletal Sciences,University of Oxford

Co-Author: – IDIAPJGol; NDORMS, University of Oxford

Co-Author: – IDIAPJGol, Barcelona, Spain

Co-Author: – Real World Solutions, IQVIA, Cambridge, MA, US)

Co-Author: – IQVIA, Cambridge, MA, USA

Co-Author: – Pharmaco- and Device Epidemiology, Centre for Statistics in Medicine - Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, Botnar Research Centre, University of Oxford, Windmill Road, Oxford

Co-Author: – Department of Medical Informatics, Erasmus University Medical Center, Rotterdam, Netherlands

Co-Author: – Erasmus University Medical Center, Rotterdam, The Netherlands

Co-Author: – CSM, NDORMS, University of Oxford

Vaccines

1:30 PM – 1:35 PM CEST

Predictors of Effectiveness of First-line Biologic Disease Modifying Antirheumatic Drug(s) (bDMARD) or Targeted Synthetic DMARD (tsDMARD) Treatment with a Tumor Necrosis Factor Inhibitor in Patients with Rheumatoid Arthritis

Location: C1M2

Presenting Author: – AbbVie

Co-Author: – AbbVie

Co-Author: – GNS Healthcare

Co-Author: – BWH Div of Pharmacoepidemiology and Pharmacoeconomics

Co-Author: – GNS Healthcare

Biologics/Biosimilars

1:35 PM – 1:40 PM CEST

Effect Modification of Biologic Survival by Patient Characteristics: A Step Towards Precision Medicine in the Treatment of Psoriasis

Location: C1M2

Presenting Author: – The University of Manchester

Co-Author: – West Glasgow Ambulatory Care Hospital, Glasgow, UK

Co-Author: – Charles Department of Dermatology, St Vincent's University Hospital, Dublin, Ireland and School of Health Sciences and Charles Institute, University College Dublin, Dublin, Ireland.

Co-Author: – Department of Dermatology, The Leeds Teaching Hospitals NHS Trust, Leeds, UK.

Co-Author: – Institute of Translational and Clinical Medicine, Newcastle University Medical School and Department of Dermatology, Royal Victoria Infirmary, Newcastle Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK.

Co-Author: – St John's Institute of Dermatology, Guy's and St Thomas' NHS Foundation Trust and King's College London, London, United Kingdom.

Co-Author: – Centre for Dermatology Research, University of Manchester, Manchester, UK.

Biologics/Biosimilars

1:40 PM – 1:45 PM CEST

Application of a Systems Biology Approach to Address Confounding by Indication for Immune-mediated Disorders in Spontaneous Reports Data: A Case Study of Vedolizumab-associated Pancreatitis in Inflammatory Bowel Disease

Location: C1M2

Presenting Author: – University of South Australia

Co-Author: – University of South Australia

Biologics/Biosimilars

1:45 PM – 1:50 PM CEST

Discontinuation of Infliximab Treatment in IBD Patients: A Comparison Between Patients Who Retransitioned to Originator and Those Who Remained on Biosimilar

Location: C1M2

Presenting Author: – Stichting Apotheek der Haarlemse Ziekenhuizen

Co-Author: – University of Utrecht

Co-Author: – Pharmacy Foundation of Haarlem Hospitals, Haarlem, the Netherlands

Co-Author: – Department of Clinical Pharmacy, Medisch Spectrum Twente, Enschede, the Netherlands

Co-Author: – Department of Gastroenterology and Hepatology, Spaarne Gasthuis, Haarlem and Hoofddorp, The Netherlands

Co-Author: – Division of Pharmacoepidemiology & Clinical Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Faculty of Science, Utrecht University, Utrecht, the Netherlands

Co-Author: – Stichting Apotheek der Haarlemse Ziekenhuizen

Biologics/Biosimilars

2:00 PM – 2:05 PM CEST

Mortality Among Parkinson's Disease Patients Treated with Pimavanserin or Atypical Antipsychotics: An Observational Study in Medicare

Location: C1M2

Presenting Author: – Acumen, LLC

Co-Author: – US Food and Drug Administration

Co-Author: – Office of Biostatistics, Center for Drug Evaluation and Research, U.S. Food and Drug Administration

Co-Author: – US Food and Drug Administration

Co-Author: – Acumen LLc

Co-Author: – Acumen LLC

Co-Author: – US Food and Drug Administration

Co-Author: – Stanford University

Co-Author: – Acumen LLC

Co-Author: – CMS

Co-Author: – US Food and Drug Administration

Benefit-Risk Assessment, Communication, and Evaluation (BRACE)

2:05 PM – 2:10 PM CEST

Post-market Safety Communication for New Drugs Approved in Australia 2010-2016

Location: C1M2

Presenting Author: – University of Sydney

Co-Author: – Australian Commission on Safety and Quality in HealthCare

Co-Author: – University of Sydney

Co-Author: – Utrecht University

Benefit-Risk Assessment, Communication, and Evaluation (BRACE)

2:10 PM – 2:15 PM CEST

Hydroxyzine initiation following drug safety advisories on cardiac arrhythmias in the UK and Canada: a longitudinal cohort study

Location: C1M2

Presenting Author: – Therapeutics Initiative, Department of Anesthesiology, Pharmacology & Therapeutics, University of British Columbia

Co-Author: – University of Sydney

Co-Author: – Utrecht University

Co-Author: – Copenhagen Centre for Regulatory Science, University of Copenhagen

Co-Author: – University of British Columbia

Co-Author: – University of South Australia

Co-Author: – Division of Pharmacoepidemiology and Clinical Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Faculty of Science, Utrecht University, 3584CG Utrecht, The Netherlands

Co-Author: – Pharmacovigilance Research Center, Department of Drug Design and Pharmacology, University of Copenhagen, Copenhagen, Denmark

Co-Author: – York University

Co-Author: – University of South Australia

Co-Author: – Dalhousie University

Co-Author: – McMaster University

Co-Author: – Centre for Big Data Research in Health, Faculty of Medicine and Health, University of New South Wales, Sydney, Australia

Co-Author: – University of British Columbia

Co-Author: – George Washington University

Co-Author: – University of Colorado Anschutz Medical Campus

Co-Author: – University of Sydney

Co-Author: – Brigham and Women’s Hospital and Harvard Medical School

Co-Author: – University of British Columbia

Benefit-Risk Assessment, Communication, and Evaluation (BRACE)

2:15 PM – 2:20 PM CEST

Duration of the evaluation of additional risk minimization measures: the need for speed

Location: C1M2

Presenting Author: – Utrecht University

Co-Author: – Medicines Evaluation Board, Utrecht, The Netherlands.

Co-Author: – Division of Pharmacoepidemiology and Clinical Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Faculty of Science, Utrecht University, 3584CG Utrecht, The Netherlands

Benefit-Risk Assessment, Communication, and Evaluation (BRACE)

2:40 PM – 3:50 PM CEST

Annual Meeting of ISPE Members & Awards Ceremony

Location: Congress Hall D4

Speaker: – UPenn Center for Pharmacoepidemiology Research & Training

Speaker: – Eli Lilly and Company

3:50 PM – 4:15 PM CEST

Break/Exhibits/Posters

Location: Hall C

4:15 PM – 5:45 PM CEST

Late Breakers (oral presentations)

Location: C1M2

Moderator: – Aarhus University

Moderator: – Harvard Pilgrim Health Care Institute

Methods in Pharmacoepidemiology

4:15 PM – 4:30 PM CEST

Alternative Approaches to Defining COVID-Related Inpatient Encounters in IBM® Marketscan® Data

Location: C1M2

Presenting Author: – Pfizer Inc

Co-Author: – Pfizer Inc

Co-Author: – Genesis Research

Co-Author: – Pfizer Inc

Co-Author: – Pfizer

Informatics

4:30 PM – 4:45 PM CEST

Use of the New ICD-10-CM Diagnosis Code for Post COVID-19 Condition in Routine Clinical Practice in the United States

Location: C1M2

Presenting Author: – Pfizer Inc

Co-Author: – Pfizer, Inc.

Co-Author: – Genesis Research

Co-Author: – Pfizer, Inc.

Co-Author: – Pfizer Inc

Health Economics/Outcomes Research

4:45 PM – 5:00 PM CEST

Rapid Surveillance on the Use of Neutralising Monoclonal Antibodies and Antivirals in Patients With COVID-19 in Scotland Using Administrative and Purposely Collected Data

Location: C1M2

Presenting Author: – University of Strathclyde

Co-Author: – Public Health Scotland

Co-Author: – University of Edinburgh

Co-Author: – Public Health Scotland

Co-Author: – University of Strathclyde

Drug Utilization Research

5:00 PM – 5:15 PM CEST

Increasing Use of Antidepressants, Hypnotics and Psychostimulants During the COVID-19 Pandemic Among Danish Children, Adolescents, and Young Adults

Location: C1M2

Presenting Author: – University of Southern Denmark (Department of Clinical Research)

Co-Author: – University of Southern Denmark

Co-Author: – National Centre for Register-based Research - Aarhus University

Co-Author: – Pharmacology and Pharmacy, Department of Public Health, University of Southern Denmark (SDU)

Co-Author: – University of Southern Denmark

Drug Utilization Research

5:15 PM – 5:30 PM CEST

Female Preconception Vaccination Against COVID-19 And Spontaneous Abortion in A Prospective Preconception Cohort Study

Location: C1M2

Presenting Author: – Boston University School of Public Health

Co-Author: – Department of Epidemiology, Boston University School of Public Health, Boston, MA, USA

Co-Author: – Harvard Medical School

Co-Author: – Harvard School of Public Health

Co-Author: – Department of Epidemiology, Boston University School of Public Health, Boston, MA, USA

Pregnancy and Lactation

5:30 PM – 5:45 PM CEST

Comparative Effectiveness of Sotrovimab and Molnupiravir for Prevention of Severe COVID-19 Outcomes in Non-hospitalised Patients: An Observational Cohort Study Using the OpenSAFELY Platform

Location: C1M2

Presenting Author: – London School of Hygiene and Tropical Medicine

Co-Author: – London School of Hygiene & Tropical Medicine

Co-Author: – Bennett Institute for Applied Data Science, Nuffield Department of Primary Care Health Sciences, University of Oxford, OX26GG

Co-Author: – Department of Medical Statistics, London School of Hygiene and Tropical Medicine

Co-Author: – Department of Non-Communicable Disease Epidemiology, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT

Co-Author: – University of Oxford

Co-Author: – The DataLab, Nuffield Department of Primary Care Health Sciences, University of Oxford, OX26GG

Co-Author: – Department of Non-Communicable Disease Epidemiology, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT

Drug Effectiveness

4:15 PM – 5:45 PM CEST

HARmonized Protocol to Enhance Reproducibility (HARPER): An ISPE-ISPOR Joint Task Force of the RWE Initiative

Location: C1M5

Presenting Author: – Harvard Medical School/Brigham & Women's Hospital

Speaker: – US Food and Drug Administration

Speaker: – Brandeis University

Speaker: – European Medicines Agency

Speaker: – Utrecht University

Methods in Pharmacoepidemiology

4:15 PM – 5:45 PM CEST

Cloning, Censoring, and Weighting — Oh My! Applications of Target Trial Emulation for Evaluating Cancer Interventions When Study Eligibility, Intervention Initiation, and Start of Follow-up Are Not Aligned

Location: Congress Hall D2

Presenting Author: – UNC Gillings School of Global Public Health

Author: – RTI Health Solutions

Author: – London School of Hygiene and Tropical Medicine

Author: – University of Illinois-Chicago

Author: – Brigham and Women's Hospital, Harvard Medical School

Author: – Daiichi Sankyo

Author: – GlaxoSmithKline

Drug Effectiveness

4:15 PM – 5:45 PM CEST

COVID-19 Vaccine Safety Monitoring: Opportunities, Challenges and Lessons Learned for Pharmacoepidemiology

Location: Congress Hall D5

Presenting Author: – RTI Health Solutions

Author: – University Medical Center Utrecht

Author: – Pfizer Inc

Author: – European Medicines Agency

Author: – TriNetX

Author: – RTI Health Solutions

Author: – US Food and Drug Administration

Author: – AstraZeneca

Author: – Moderna

Author: – Janssen Research & Development

Vaccines

4:15 PM – 5:45 PM CEST

Drug Safety on the Cutting Edge: What are the Implications of EMA's To-Be-Released Risk Minimisation Guidance on Pharmacoepidemiological Methods and Practice in Developed and Developing Countries?

Location: C1M0

Presenting Author: – Evidera | PPD

Author: – European Medicines Agency

Author: – Loyola University Chicago

Author: – Botswana Medicines Regulatory Authority

Benefit-Risk Assessment, Communication, and Evaluation (BRACE)

4:15 PM – 5:45 PM CEST

Real-World Evidence Studies in the post-COVID-19 Era: Methodological Considerations for Pandemic Related Disruptions

Location: C1M1

Presenting Author: – Washington University School of Medicine

Author: – Merck & Co., Inc.

Author: – University of Utrecht

Author: – JHSPH Center for Drug Safety & Effectiveness

Methods in Pharmacoepidemiology

6:00 PM – 7:00 PM CEST

Council Meetings

7:00 PM – 11:00 PM CEST

Social Evening at the Langelinie Pavillonen